BCR-ABLp190 Fusion detection Qualitative One Step RT-PCR Kit for ALL, CML, (rare cases)

CML is created following the translocation of the interaction between chromosome 9 and 22, during which ABL oncogene on chromosome 9 is transferred to the BCR region of chromosome 22. The resulting chromosome, called the Philadelphia chromosome, encodes an abnormally active tyrosine kinase protein that is always active, resulting in an increase in white blood cells in the bone marrow. Currently, the most sensitive method for identifying CML is the “Qualitative Reverse Copying of Polymerase Chain Reactions (RT-PCR)”.